In this project, we aim to evaluate the epidemiology of persistent hrHPV infection in a cohort of East African and West African women. This project also evaluates other potential biomarkers of persistent hrHPV infection and progression to cervical cancer. Participants are recruited from women who volunteer at the cervical cancer screening clinics at participating hosptials and meet the eligibility criteria.
The Maverick Study
This project is focused on the study of the vaginal microenvironment and the discovery of biomarkers in the microenvironment that may be associated with cervical cancer or persistent hrHPV infection. Participants for this study are drawn from the EPIC-Biomarker Study.
The Gene-Disc study
This project is focused on the discovery of genes related to persistent hrHPV infection, cervical cancer and other biomarkers identified in the EPIC-Biomarker and Maverick Studies. We conduct genome-wide association studies and candidate gene association studies. This project will be linked to the NIH CIDR and genome sequencing facilities. It will contribute data to the African Genome Variation Project.
This is the administrative arm of the ACCME study. It provides administrative management and oversight of the grant. It also helps to foster research activities at collaborating institutions and provides training in grants and manuscript writing and research administration which helps to empower ACCME scientists ti be competitive and ensure sustainability of ACCME
This is the Training, Capacity Development and Technology Transfer Project (TRACAD). It provides post-doctoral training to qualified African scientists through a rigorous and competitive pan-African candidate selection process. It also conduct short and medium term, local and international sandwich trainings in research methods, epidemiology, bioinformatics, biostatistics and data management, laboratory methods, social and behavioral research for African scientists at the IHVN, Abuja, Nigeria; CIDRZ, Lusaka, Zambia; and the AUST, Abuja, Nigeria.